Possible Signs and Symptoms of Gluten Intolerance

Following is a list of the possible signs and symptoms of celiac disease and gluten intolerance. Obviously, every person is different and may manifest different symptoms or any combination of these symptoms.


The most common signs and symptoms include: 

  • Fatigue
  • Gastrointestinal distress (gas, bloating, diarrhea, constipation, vomiting, reflux)
  • Headaches (including migraines)
  • Numbness and Tingling in the legs
  • Seizures
  • Infertility
  • Mouth sores (canker sores)
  • Weight loss or gain
  • Inability to concentrate
  • Moodiness
  • Depression
  • Amenorrhea (Lack of Menstrual Period)
  • Delayed Menarche (Delayed first Menstrual cycles)
  • Bone Pain
  • Joint Pain
  • Muscle Pain
  • Dental enamel hypoplasia
  • Short stature

Symptoms also include:

  • Abnormal liver test
  • Aching joints
  • Addison’s disease
  • Alopecia
  • Anemia
  • Ataxia
  • Autoimmune hepatitis
  • Chronic abdominal pain
  • Chronic fatigue
  • Cramps
  • Crohn’s disease
  • Dermatitis herpetiformis
  • Eczema
  • Epilepsy
  • Family history of celiac disease
  • Failure to thrive (infants)
  • Fat in the stools (due to poor digestion)
  • Gall bladder disease
  • Hyperthyroidism/hypothyroidism
  • Total IgA deficiency
  • Insulin-dependent diabetes (type 1)
  • Infertility
  • Iron deficiency
  • Irregular menstrual cycle
  • Irritability and behavioral changes
  • Irritable Bowel Syndrome (IBS)
  • Low Birth-Weight Babies
  • Malnutrition
  • Miscarriages & Spontaneous Abortions
  • Multiple sclerosis
  • Non-Hodgkin’s lymphoma
  • Numbness and tingling
  • Osteoporosis, osteopenia, osteomalacia
  • Pancreatic disorders
  • Pathologic fractures
  • Peripheral neuropathy
  • Primary biliary cirrhosis
  • Psoriasis
  • Recurrent stomach pain
  • Rheumatoid arthritis
  • Sjögren syndrome
  • Systemic lupus
  • Turner syndrome
  • Ulcerative colitis
  • Vitiligo
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